Skip to Main Content
Person painting a mural representing possibilitiesIcon of shield with text 'Proven kidney preservation. FDA approved'

For adults with primary IgA nephropathy

WITH FILSPARI®
I CAN SEE MY POSSIBILITIES

Learn about FILSPARI

Not an actual patient.

FILSPARI is proven to powerfully lower proteinuria and preserve kidney function by working directly in the kidneys

Is FILSPARI right for me?

Learn about FILSPARI and how it has helped others with IgA nephropathy.

Learn more about FILSPARI

FILSPARI Assistance

Find out if you may be eligible to pay as little as $0 per month.*

See terms and conditions.

Find support

Starting FILSPARI?

There are 3 steps to upgrade your treatment.

See the steps

*Program only valid for patients with commercial or private insurance. Must be a US resident. Not valid for patients insured by a federal or state government-funded health plan, including Medicare, Medicare Advantage, Medicaid, and TRICARE, or uninsured patients. See full terms and conditions.

SEE MORE

Important Safety Information

IMPORTANT SAFETY
INFORMATION

What is the most important information I should know about FILSPARI?

FILSPARI is only available through the FILSPARI Risk Evaluation and Mitigation Strategy (REMS) Program because of the serious risk of liver problems and serious birth defects. Before you begin treatment with FILSPARI, you must read and agree to all the instructions in the FILSPARI REMS Program.

FILSPARI can cause changes in liver tests. Liver failure was not observed in people treated with FILSPARI in clinical studies, but some medicines that are like FILSPARI can cause liver failure. Your healthcare provider will do blood tests to check your liver before starting FILSPARI, monthly for the first 12 months, then every three months during treatment. Your healthcare provider may temporarily stop or permanently stop treatment with FILSPARI if you have changes in your liver tests.

Stop taking FILSPARI right away if you develop any of the following signs of liver problems during treatment with FILSPARI: nausea or vomiting, pain on the upper right side of your stomach area, tiredness, loss of appetite, yellowing of the skin or the whites of your eyes (jaundice), dark “tea-colored” urine, fever, or itching.

FILSPARI can cause serious birth defects if taken during pregnancy. Patients must not be pregnant when they start taking FILSPARI, become pregnant during treatment, or for one month after stopping treatment. Patients who can become pregnant must have a negative pregnancy test before starting FILSPARI, monthly during treatment, and for one month after stopping FILSPARI.

Patients who can become pregnant must use effective birth control before starting treatment with FILSPARI, during treatment with FILSPARI, and for one month after stopping FILSPARI because the medicine may still be in your body.

  • If you have had a tubal sterilization or have an IUD (intrauterine device) or progesterone implant, these methods may be used alone, and no other form of birth control is needed.
  • Talk with your healthcare provider or gynecologist (a healthcare provider who specializes in reproduction) to find out about options for effective forms of birth control that you may use to prevent pregnancy during treatment with FILSPARI.
  • If you decide that you want to change the form of birth control that you use, talk with your healthcare provider or gynecologist to be sure that you choose another effective form of birth control.
  • Do not have unprotected sex. Talk to your healthcare provider or pharmacist right away if you have unprotected sex or if you think your birth control has failed. Your healthcare provider may talk with you about using emergency birth control.
  • Tell your healthcare provider right away if you miss a menstrual period or think you may be pregnant.

Do not take FILSPARI if you:

  • are pregnant, plan to become pregnant, or become pregnant during treatment with FILSPARI. FILSPARI can cause serious birth defects.
  • are taking any of these medicines: an angiotensin receptor blocker, an endothelin receptor antagonist, or aliskiren. Ask your healthcare provider or pharmacist if you are not sure if you take one of these medicines.

Before taking FILSPARI, tell your healthcare provider about all of your medical conditions, including if you have liver problems, are pregnant or plan to become pregnant during FILSPARI treatment, or are breastfeeding or plan to breastfeed as it is not known if FILSPARI passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during FILSPARI treatment.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, grapefruit, and antacid medicines. FILSPARI and other medicines may affect how each other works and cause side effects. Do not start any new medicine until you check with your healthcare provider.

Especially tell your healthcare provider if you take:

  • nonsteroidal anti-inflammatory drugs (NSAIDs)
  • potassium-containing medicines, potassium supplements or salt substitutes containing potassium
  • blood pressure medicines
  • H2 receptor blocker medicine or proton pump inhibitor (PPI) medicine

Ask your healthcare provider or pharmacist if you are not sure if you take one of these medicines.

What are the possible side effects of FILSPARI?

FILSPARI can cause serious side effects, including:

  • Liver problems. See Medication Guide – What is the most important information I should know about FILSPARI?
  • Serious birth defects. See Medication Guide – What is the most important information I should know about FILSPARI?
  • Low blood pressure. This is common during treatment with FILSPARI and can also be serious. Tell your healthcare provider if you feel dizzy, light-headed, or faint. Stay hydrated during treatment with FILSPARI.
  • Worsening of kidney function. Your healthcare provider will check your kidney function during treatment with FILSPARI.
  • Increased potassium in your blood. This is common during treatment with FILSPARI and can also be serious. Your healthcare provider will check your potassium blood level during treatment with FILSPARI.
  • Fluid retention. FILSPARI can cause your body to hold too much water. Tell your healthcare provider right away if you have any unusual weight gain or swelling of your ankles or legs.

The most common side effects of FILSPARI include: swelling of the hands, legs, ankles, and feet (peripheral edema), dizziness, and low red blood cells (anemia). These are not all the possible side effects of FILSPARI. Call your doctor for medical advice about side effects.

You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Travere Therapeutics at 1-877-659-5518.

For additional Important Safety Information, including serious side effects, please see the Medication Guide.

WHAT IS FILSPARI® (sparsentan)?

FILSPARI is a prescription medicine used to slow kidney function decline in adults with a kidney disease called primary IgA nephropathy (IgAN), who are at risk for their disease getting worse. It is not known if FILSPARI is safe and effective in children.

The link you have selected will direct you to a website
outside of FILSPARI.com